Figure 6. Gene Set Enrichment Analysis (GSEA) and Gene Ontology (GO) of corresponding functions and signaling pathways associated with POP1 expression. (A–H) The POP1 expression was significantly correlated with the E2F target, G2M checkpoint, interferon-gamma response, mitTORC1 signaling, and MYC targets. (I) The differentially expressed genes between the high- and low-POP1 groups were mainly enriched in organelle fission, nuclear division, and chromosome segregation. Abbreviations: GSEA, Gene set enrichment analysis; GO, Gene Ontology.