Research Paper Volume 14, Issue 15 pp 6269—6298
The comprehensive expression and functional analysis of m6A modification “readers” in hepatocellular carcinoma
Figure 14. Validation the functions of IGF2BP3 in HCC cell line. (A) The knock-down efficiency of IGF2BP3 mRNA expression in Hep3B cell. (B) The knock-down efficiency of IGF2BP3 protein expression in Hep3B cell. (C) The representative migration images of IGF2BP3 stably KD and NC Hep3B cells. (D) The statistical analysis of migration assay for Hep3B cells with IGF2BP3 stably KD and NC. *P < 0.05; ***P < 0.001; and ****P < 0.0001. (E) The representative sphere formation assay images of IGF2BP3 stably KD and NC Hep3B cells. (F) The statistical analysis of sphere formation assay for Hep3B cells with IGF2BP3 stably KD and NC. *P < 0.05; ***P < 0.001; and ****P < 0.0001.