Research Paper Volume 14, Issue 15 pp 6094—6110
miRNA-338-3p inhibits the migration, invasion and proliferation of human lung adenocarcinoma cells by targeting MAP3K2
Figure 7. Overexpressed miR-338-3p affects the expression of proteins related to migration and invasion function of NCI-H1299 and A549 cells through the ERK pathway. (A) Protein expression levels of p-ERK1/2, t-ERK1/2, MMP-2, MMP-3 and MMP-9 in NCI-H1299 and A549 cells. (B) Statistical analysis results of protein expressions in NCI-H1299 and A549 cells. **P < 0.01, ##P < 0.01 and $$P < 0.01 mean that the difference is statistically significant.