Research Paper Volume 14, Issue 13 pp 5464—5477
Curcumin analogue BDDD-721 exhibits more potent anticancer effects than curcumin on medulloblastoma by targeting Shh/Gli1 signaling pathway
Figure 3. Effects of BDDD-721 and curcumin on cell migration and invasion of medulloblastoma cells. (A) Cell migration ability was analyzed by Transwell assay without coated Matrigel. (B) Cell invasion ability was measured by Transwell assay with coated with Matrigel. (C) MMP-2 and MMP-9 proteins were detected by western blot after 20 μM curcumin or BDDD-721 treatment for 24h.