Research Paper Volume 14, Issue 13 pp 5449—5463

Long non-coding RNA H19 contributes to spinal cord ischemia/reperfusion injury through increasing neuronal pyroptosis by miR-181a-5p/HMGB1 axis

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Figure 7. Downregulation of H19 alleviates SCI/R injury in SCI/R mice. (A) H&E, Evans Blue Extravasation, and Nissl staining (× 200) were investigated in mice after SCI/R for 48 h. (B) The locomotor function of the hind limbs was investigated by the BMS score in mice after SCI/R for 48 h. EB (C) and Nissl positive cells (D) were analyzed quantitatively, respectively. The results were presented as the mean ± SD. N = 10; *P<0.05.