Research Paper Volume 14, Issue 11 pp 4897—4913

Effects of STAT3 on aging-dependent neovascularization impairment following limb ischemia: from bedside to bench

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Figure 1. Impaired angiogenesis of aged mice post hindlimb ischemia surgery. (A) The study design of limb ischemia in young (10 w/o) and aged (80–100 w/o) mice. (B) Representative images of laser Doppler perfusion flow in limb ischemia in young and aged mice. (C) Representative images and weight quantifications of harvested ischemic (left) limbs compared with nonischemic (right) limbs. N = 6, *P < 0.05.