Figure 1. Impaired angiogenesis of aged mice post hindlimb ischemia surgery. (A) The study design of limb ischemia in young (10 w/o) and aged (80–100 w/o) mice. (B) Representative images of laser Doppler perfusion flow in limb ischemia in young and aged mice. (C) Representative images and weight quantifications of harvested ischemic (left) limbs compared with nonischemic (right) limbs. N = 6, *P < 0.05.