An active ingredient isolated from <i>Ganoderma lucidum</i> promotes burn wound healing via TRPV1/SMAD signaling

Chunwei Jiao; Hao Yun; Huijia Liang; Xiaodong Lian; Shunxian Li; Jiaming Chen; Javeria Qadir; Burton B. Yang; Yizhen Xie

doi:doi:10.18632/aging.204119

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Research Paper Volume 14, Issue 13 pp 5376—5389

An active ingredient isolated from Ganoderma lucidum promotes burn wound healing via TRPV1/SMAD signaling

Figure 6. Analysis of SMAD2/3 and TRPV1 expression in mouse skin burn. (A) Western blot (upper) and quantitative analyses (lower) of SMAD2/3 and p-SMAD2/3. (B) Immunofluorescence staining of SMAD2/3 nuclear translocation on LPS (1 μg/mL) induction. Scale bar=200 μm. (C) Immunofluorescence staining of TRPV1 expression in skin burn upon GLSO treatment. Scale bar=200 μm. The data are presented as the mean ± SD. ^*P<0.05 versus sham.