Research Paper Volume 14, Issue 11 pp 4874—4887
Effective natural inhibitors targeting IGF-1R by computational study
Figure 2. The 2D structures of natural compounds selected from virtual screening by ChemDraw. And Pharmacophore predictions using 3D-QSAR. (A) ZINC38433168; (B) ZINC000014946303; (C) ZINC000006003042. (D) ZINC000014946303: Green represents hydrogen acceptor, blue represents hydrophobic center, purple represents hydrogen donor, and yellow represents ring aromatic. (E) ZINC000006003042: Green represents hydrogen acceptor, blue represents hydrophobic center, purple represents hydrogen donor, and yellow represents ring aromatic.