Research Paper Volume 14, Issue 11 pp 4786—4818
Identification of prognostic candidate signatures by systematically revealing transcriptome characteristics in lung adenocarcinoma with differing tumor microenvironment immune phenotypes
Figure 10. Evaluation of prognostic signature. (A) Survival curve based on GSE31210 dataset. LUAD patients in the low-risk group had a higher OS rate than that in the high-risk group (p=0.00103, HR=0.30307, 95% CI=0.1409-0.6441). (B) ROC curve based on GSE31210 dataset. The AUCs of 2-, 3-, 4- and 5-year associated with the survival were separately 0.7386, 0.6661, 0.7121 and 0.6971. (C) Survival curve based on GSE50081 dataset. LUAD patients in the low-risk group had a higher OS rate than that in the high-risk group (p=0.04858, HR=0.63122, 95% CI=0.3969-1.0009). (D) ROC curve based on GSE50081 dataset. The AUCs of 2-, 3-, 4- and 5-year associated with the survival were separately 0.599, 0.584, 0.5561 and 0.5858. LUAD, lung adenocarcinoma; OS, overall survival; HR, hazard rate; ROC, receiver operating characteristic; AUC, area under the curve; CI, confidence interval.