Research Paper Volume 14, Issue 18 pp 7328—7347

Establishment and validation of individualized clinical prognostic markers for LUAD patients based on autophagy-related genes

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Figure 1. Simple flow chart of this study. TCGA-LUAD and GSE68465 cohorts were used for analysis in this study. Training cohorts were used to detect prognostic genes. Lasso regression model was used to establish prognostic signatures based on prognostic genes. We then confirmed the expression patterns of EIF2AK3 and ITGB1 in LUAD cell lines.