Research Paper Volume 14, Issue 9 pp 4137—4157
LncRNA CRART16/miR-122-5p/FOS axis promotes angiogenesis of gastric cancer by upregulating VEGFD expression
Figure 5. RNA profiling of CRART16-overexpressing gastric cancer. (A) Heatmaps of microRNAs (miRNAs) showing the top differentially expressed genes between SGC-CRART16 and SGC-NC cells (n = 3). (B) A volcano plot showing the differentially expressed individual miRNAs in SGC-CRART16 cells. The miRNAs significantly upregulated in the SGC-CRART16 group are shown in red; the miRNAs significantly downregulated are shown in green. (C) Venn diagram showing the intersection of differentially expressed miRNAs from gastric cancer and colon cancer cell lines with the potential miRNA targets from miRwalk prediction. The most probable target of CRART16 was identified to be miR-122-5p. (D) Heatmaps of mRNAs showing the top differentially expressed genes between SGC-CRART16 and SGC-NC cells (n = 3).