RecQ mediated genome instability 2 (<i>RMI2</i>): a potential prognostic and immunological biomarker for pan-cancers

Wei Wei; Xiaomei Ying; Liang Chen; Qingmei Sun; Xiaohuan Lu; Yang Xia; Rubin Xu; Zhechen Zhu; Dong Zhang; Qikai Tang; Li Li; Jiaheng Xie; Hongzhu Yu

doi:doi:10.18632/aging.204076

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Research Paper Volume 14, Issue 9 pp 4107—4136

RecQ mediated genome instability 2 (RMI2): a potential prognostic and immunological biomarker for pan-cancers

Figure 10. Further validation of RMI2 in other databases. (A) Expression analysis in ICGC database showed that RMI2 was up-regulated in hepatocellular carcinoma (P<0.001). (B) ROC curve showed that the AUC value of RMI2 in hepatocellular carcinoma was 0.849. (C) Survival analysis showed that high RMI2 expression was associated with poor prognosis of hepatocellular carcinoma. (D–F) The correlation between RMI2 and stage, age, and gender of HCC patients. (G) Univariate COX regression. (H) Multivariate COX regression. (I, J) RMI2 was significantly correlated with IL1B and TNFSF10 (P<0.05, Figure 10I, 10J).