Research Paper Volume 14, Issue 13 pp 5366—5375
High TRB3 expression induces chondrocyte autophagy and senescence in osteoarthritis cartilage
Figure 4. Chondrocyte autophagy is dependent on TRB3. (A, B) Protein expression of TRB3, P62, Beclin 1 and LC3 in isolated chondrocytes from young healthy treated with TNF-α, TRB3 siRNA or control siRNA. (C) Chondrocyte autophagic activity was detected by Immunofluorescence of P62 and MDC staining. The results are described as the mean ± SD. *P < 0.05, **P < 0.01 vs. normal group.