Research Paper Volume 14, Issue 7 pp 3293—3312
Abnormal phenotype of Nrf2 is associated with poor prognosis through hypoxic/VEGF-A-Rap1b/VEGFR2 pathway in gastric cancer
Figure 9. Relative expression of mRNA and the phosphorylation of protein (A) Expression of VEGFR2 in GC cells after they were transfected with negative control siRNA or VEGFR2 siRNAs (siVEGFR2-366, siVEGFR2-633 and siVEGFR2-990). (B) Expression of VEGF-A in GC cells cultured under a hypoxic condition. (C) Expression of Erk, P-Erk, Akt and P-Akt in GC cells after transfected with siRap1b or siVEGFR2 (left) Hypoxia (right) VEGF-A. (*P<0.05, **P<0.001).