Research Paper Volume 14, Issue 7 pp 3293—3312
Abnormal phenotype of Nrf2 is associated with poor prognosis through hypoxic/VEGF-A-Rap1b/VEGFR2 pathway in gastric cancer
Figure 6. Effects of Nrf2 or (and) Rap1b knockdown on the regulation of the GC invasion capacity under a hypoxic condition. The invasion capacity was suppressed in GC cells transfected with siNrf2RNA-1498 or (and) siRap1bRNA-501 under hypoxic conditions. (A) Negative control; (B) siRap1bRNA; (C) siNrf2RNA; (D) siRap1bRNA and siNrf2RNA; (E) The graph shows the quantified data of the assay. (*P<0.05, **P<0.001).