Research Paper Volume 14, Issue 7 pp 3293—3312

Abnormal phenotype of Nrf2 is associated with poor prognosis through hypoxic/VEGF-A-Rap1b/VEGFR2 pathway in gastric cancer

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Figure 1. Immunohistochemical expression of Nrf2 and heme oxygenase-1 (HO-1) in gastric cancer (GC) and para-carcinoma tissues. (A) Slides without primary antibody served as the negative control in GC tissues. (B) Typical immunohistologic features with Nrf2 expression in GC tissues. The Nrf2 staining localized predominantly in the nucleus. (C) Typical immunohistologic features with HO-1 expression in GC tissues. (D) Typical immunohistologic features with Nrf2 expression in para-carcinoma tissues. Magnifications, ×200.