Research Paper Volume 14, Issue 7 pp 3259—3275

Cholesterol-induced leucine aminopeptidase 3 (LAP3) upregulation inhibits cell autophagy in pathogenesis of NAFLD

class="figure-viewer-img"

Figure 6. LAP3 was upregulated in the plasma of NAFLD patients. (A and B) The LAP3 expression in plasma of NAFLD patients and normal people was detected by western blotting (A) and normalized by serum total protein (B). (CH) Correlation analysis between LAP3 and clinical indexes of NAFLD by Graph prism 8.0. Data were presented as means ± SD. *p < 0.05; **p < 0.01; ***p < 0.001. A two-tail t-test was performed to determine the statistical significance. Abbreviations: NAFLD: Nonalcoholic fatty liver disease; NC: normal healthy control; GGT: γ-glutamyltranspeptidase; ALP: alkaline phosphatase; TG: triglyceride; HDL: high-density lipoprotein; LDL: low-density lipoprotein.