Cholesterol-induced leucine aminopeptidase 3 (LAP3) upregulation inhibits cell autophagy in pathogenesis of NAFLD

Lina Feng; Yanping Chen; Ke Xu; Yingchao Li; Farooq Riaz; Kaikai Lu; Qian Chen; Xiaojuan Du; Litao Wu; Dan Cao; Chunyan Li; Shemin Lu; Dongmin Li

doi:doi:10.18632/aging.204011

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Research Paper Volume 14, Issue 7 pp 3259—3275

Cholesterol-induced leucine aminopeptidase 3 (LAP3) upregulation inhibits cell autophagy in pathogenesis of NAFLD

Figure 3. Bioinformatic analysis indicated that LAP3 played a significant role in GSH metabolism. (A–C) Analysis of top ten proteins that interact with LAP3 in human, rat, and mouse using the STRING database. (D) Screened pathway showing the involvement of LAP3 in GSH metabolism using KEGG database.