Research Paper Volume 14, Issue 4 pp 1865—1878
miR-223-3p inhibits the progression of atherosclerosis via down-regulating the activation of MEK1/ERK1/2 in macrophages
Figure 2. Prevention of AS progression by miR-223-3p mimics. (A) Representative Movat staining of the histopathology of mice's carotid roots and a pronounced decrease in the extent of atherosclerotic lesions in the carotid roots tissues from miR-223-3p mimics. (*P<0.05). (B) The plaque area staining positive for macrophages (CD68) in the miR-223-3p mimics group and NC group (*P<0.05). (C) The SMA staining in mice's aortic roots in the miR-223-3p mimics group and NT group (*P<0.05). (D) TNF-α staining in mice's aortic roots in the miR-223-3p mimics group and NT group(*P<0.05).