Research Paper Volume 14, Issue 4 pp 1848—1864

Figure 3. Schematic drawing of interactions between ligands and Caspase-1 by Schrodinger and Pymol. Hydrogen bonds, Salt Bridges, and Hydrophobic bonds are shown in green, orange, and gray. The amino acids in the binding pocket; the amino acids that form the bonds; the bond lengths are labeled. The bonding amino acids are in the form of dark blue sticks. (A) ZINC000004099068- Caspase-1 complex: Structures and net electron cloud structures of ZINC000004099068 are shown in purple sticks. (B) ZINC000100634116- Caspase-1 complex: Structures and net electron cloud structures of ZINC000100634116 are shown in green sticks. (C) Belnacasan - Caspase-1 complex: Structures and net electron cloud structures of Belnacasan are shown in orange sticks.