Research Paper Volume 13, Issue 24 pp 25920—25930

LDH-A inhibitors as remedies to enhance the anticancer effects of PARP inhibitors in ovarian cancer cells

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Figure 4. Oxamate enhanced the tumor suppression effect of PARP inhibitors on ovarian cancer cells. (AD) Tumor volumes of xenograft tumor with oxamate and/or PARP inhibitors (olaparib or AG14361) treatment. (EH) Survival time of xenograft tumor models with oxamate and/or PARP inhibitors (olaparib or AG14361) treatment were recorded. Mean ± SEM, *P < 0.05, **P < 0.01, ns: no significance.