Research Paper Volume 13, Issue 24 pp 25920—25930
LDH-A inhibitors as remedies to enhance the anticancer effects of PARP inhibitors in ovarian cancer cells
Figure 3. Oxamate suppressed the proliferation, migration, and invasion ability of both A2780 and SKOV3 cells. (A, B) Expression of LDH-A in A2780 and SKOV3 cells after oxamate treated for 24 hours. (C, D) Proliferation rates of A2780 and SKOV3 cells were evaluated by CCK-8 assays. (E, F) Scratch assays were used to test migration ability of A2780 and SKOV3 cells after oxamate treated for 48 hours. (G, H) Images of metastatic tumor cells were recorded by microscope. (I, J) Number of invaded cells were counted under the microscope. Mean ± SEM, **P < 0.01, *** P < 0.005.