Research Paper Volume 13, Issue 23 pp 25325—25341
Artesunate treatment ameliorates ultraviolet irradiation-driven skin photoaging via increasing β-catenin expression
Figure 3. Art treatment ameliorates UVB irradiation-induced cell senescence and has no toxic side effects on normal HaCaT cells. (A) CCK-8 of the growth rate of HaCaT cells in control group, 20 μg/ml Art group, UV group, UV + 20 μg/ml Art group. (B, C) Flow cytometry of apoptotic levels in each group. (D, E) Hoechst/PI staining for morphological changes of HaCaT cell apoptosis in each group. Scale bar: 100 μm. Magnification: 200×. (F, G) SA-β-gal staining for cell senescence in each group. Scale bar: 100 μm. Magnification: 200×. **p<0.01; ***p<0.001; ****p<0.0001.