Research Paper Volume 13, Issue 23 pp 25138—25152
LncRNA SNHG3 promotes gastric cancer cell proliferation and metastasis by regulating the miR-139-5p/MYB axis
Figure 2. SNHG3 knockdown suppresses gastric cancer cell growth and metastasis. (A) SNHG3 expression was assessed in MGC-803 and HGC-27 cells following sh-SNHG3 transfection. *P<0.01 vs. sh-NC group. (B) Transfected cell proliferation was assessed via CCK-8 assay. *P<0.01, **P<0.05 vs. sh-NC group. (C) Cell cycle progression was assessed via flow cytometry following SNHG3 silencing in MGC-803 and HGC-27 cells. (D, E) MGC-803 and HGC-27 cell colony formation activity was assessed following SNHG3 silencing. *P<0.01 vs. sh-NC group. (F–I) Transwell migration and invasion assays were used to assess MGC-803 and HGC-27 cells following SNHG3 silencing. *P<0.01 vs. sh-NC group.