Research Paper Volume 13, Issue 20 pp 23603—23619

Figure 7. XAV939 significantly reversed the influence of resveratrol on apoptosis after SCI. (A) The apoptosis level in the tissue was detected using TUNEL staining; (B) The apoptosis level in the tissue was analyzed; (C) The expression of Bax was measured in the tissues; (D): The expression of Cleaved Caspase-3 was measured in the tissues; (E): The expression of Bcl-2 was measured in the tissues; (F): The levels of Bax, Cleaved Caspase-3, and Bcl-2 was analyzed; (G): The cell apoptosis model was established by H₂O₂; (H): The remarkable increased apoptosis level induced by H₂O₂ was suppressed by resveratrol; (I) The decreased cell proliferation ability caused by H₂O₂ was promoted by resveratrol. *P <0.05 compared with group SCI or H₂O₂, + P <0.05 compared with group SCI+resveratrol. The experiments were repeated at least 3 independent times.