The upregulated expression of RFC4 and GMPS mediated by DNA copy number alteration is associated with the early diagnosis and immune escape of ESCC based on a bioinformatic analysis

Jing Wang; Fei-Fei Luo; Tie-Jun Huang; Yan Mei; Li-Xia Peng; Chao-Nan Qian; Bi-Jun Huang

doi:doi:10.18632/aging.203520

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Research Paper Volume 13, Issue 17 pp 21758—21777

The upregulated expression of RFC4 and GMPS mediated by DNA copy number alteration is associated with the early diagnosis and immune escape of ESCC based on a bioinformatic analysis

Figure 8. Exploration of the mechanism of RFC4 and GMPS based on GSEA and correlation analysis. (A, B) KEGG pathway analysis of RFC4 and GMPS based on GSEA. (C, D) Correlation coefficient analysis of RFC4 and GMPS in esophageal carcinoma. (E) Correlation between RFC4 and GMPS in TCGA. (F) Correlation between RFC4 and GMPS in 46 tumor samples. ^*p < 0.05, ^**p < 0.01, ^***p < 0.001.