Figure 6.DNTs promoted NLRP3 inflammasome activation and inflammatory response in intestinal macrophages. (A–B) Detection of the expression of NLRP3 and Caspase-1 by IF staining (n = 3): NLRP3 and Caspase-1 was not expressed in the Con group, and the expression level was up-regulated after co-culture with DNTs. (C) Effect of DNTs on macrophage activation and the expression of inflammatory factors (, n = 3): the level of inflammatory factors in the Con group was low. Comparison with Con group, *P < 0.05. (D–E) Effect of NLRP3 inflammasome and related protein expression (, n = 3): DNTs co-culture significantly activated the expression of NLRP3 inflammasome related proteins, comparison with the Con group, *P < 0.05.
