Research Paper
Circular RNA LPAR3 enhances GPX4 expression by targeting miR-196a-5p to suppress ferroptosis of osteosarcoma cells
Figure 5. MiR-196a-5p contributes to osteosarcoma cell ferroptosis involving GPX4. (A, B) MTT assays analyzed cell viability in the U2OS and MG63 cells co-treated with miR-196a-5p mimic and erastin (5 mmol/L) or DMSO. (C–E) The analysis was performed in the U2OS and MG63 cells treated with miR-196a-5p mimic. The levels of iron (C), Fe2+ (D), and lipid ROS (E) were analyzed by the corresponding measurement kits. ** P < 0.01.