Figure 3. Differentially expressed genes in culture system with or without serum. (A) Hierarchical cluster showing the genes differentially expressed between the two groups. Significant genes (fold change of 2.0 and p < 0.05.) are shown in the heatmap. (B) The volcano plot shows 839 genes differentially expressed (578 genes upregulated (red) and 261 downregulated (green) in serum condition).