Figure 9 — Combined treatment with C16 peptide and angiopoietin-1 confers neuroprotection and reduces inflammation in 3-nitropropionic acid-induced dystonia mice

Research Paper|Volume 13, Issue 14|pp. 19048–19063

Combined treatment with C16 peptide and angiopoietin-1 confers neuroprotection and reduces inflammation in 3-nitropropionic acid-induced dystonia mice

Back to articleFigure 9(9 of 13)

100%

Figure 9.(A–F) Treatment with C16+Ang-l can alleviate 3-NP-induced permeability of the blood-brain barrier (leakage of Evans Blue dye, red) and loss of tight junctions (ZO-1 immunostaining, green) in the (A, D) control, (B, E) 3-NP, and (C, F) 3-NP+C16+Ang-1 groups. Scale bar = 100 μm. (G, H) Semi-quantitative profiles of (G) Evans Blue staining and (H) ZO-1 immunostaining. ^aP < 0.05 versus control; ^bP < 0.05 versus 3-NP-treated mice.