Research Paper Volume 13, Issue 14 pp 18740—18756

MicroRNA-106b-5p inhibits growth and progression of lung adenocarcinoma cells by downregulating IGSF10

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Figure 7. Identification of differentially expressed mRNAs and miRNAs in LUAD tissues and their functional enrichment analysis. (A) Volcano map shows differentially expressed mRNAs (DEG- mRNAs) in the TCGA-LUAD dataset. (B) Volcano map shows differentially expressed miRNAs (DEG- miRNAs) in the TCGA-LUAD dataset. (C) Heat map shows expression levels of DEG- mRNAs in TCGA-LUAD dataset. (D) Heat map shows expression levels of DEG- miRNAs in TCGA-LUAD dataset. (E) KEGG pathway analysis of DEG- mRNAs shows the top 12 upregulated pathways in LUAD tissues of the TCGA dataset. (F) Gene ontology analysis of DEG-mRNAs shows the top 12 biological processes in LUAD tissues of the TCGA dataset.