Interleukin-2 inducible T-cell kinase: a potential prognostic biomarker and tumor microenvironment remodeling indicator for hepatocellular carcinoma

Binhua Pan; Modan Yang; Xuyong Wei; Wangyao Li; Kun Wang; Mengfan Yang; Di Lu; Rui Wang; Beini Cen; Xiao Xu

doi:doi:10.18632/aging.203306

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Research Paper Volume 13, Issue 14 pp 18620—18644

Interleukin-2 inducible T-cell kinase: a potential prognostic biomarker and tumor microenvironment remodeling indicator for hepatocellular carcinoma

Figure 7. Validation of ITK’s prognostic capacity. 176 pairs of HCC tumor and paracarcinoma tissues were obtained from our medical center and ITK expression levels were evaluated using IHC analysis. (A) KM survival curves for the post-operation OS of low/high ITK subgroups (p = 0.024). (B) KM survival curves for the post-operation RFS of low/high ITK subgroups (p < 0.001). (C) IHC of ITK expression.