Research Paper Volume 13, Issue 13 pp 17830—17846
Linc00941 regulates esophageal squamous cell carcinoma via functioning as a competing endogenous RNA for miR-877-3p to modulate PMEPA1 expression
Figure 6. Overexpression of PMEPA1 attenuated the suppressive effects of linc00941 knockdown on ESCC cell progression. (A) Colony formation assay, (B) CCK-8 assay and (C) EdU assay determined the KYSE-510 cell proliferation. KYSE-510 cells were co-transfected with NC_si + pcDNA, linc00941_si + pcDNA, or linc00941_si + PMEPA1. (D) Transwell invasion assay and (E) wound healing assay determined the KYSE-510 cell invasion and migration. KYSE-510 cells were co-transfected with NC_si + pcDNA, linc00941_si + pcDNA, or linc00941_si + PMEPA1. N = 3. *P<0.05, **P<0.01 and ***P<0.001 compared between different treatment groups.