Figure 1.Elevated PAX4 mRNA and protein expression in both GC tissues and cell lines. (A, B) Higher PAX4 mRNA and protein expression in GC tissues compared to normal tissues (n = 60) by qRT-PCR (P < 0.0001) and WB (P = 0.0002). (C) The IHC results between GC and non-GC tissues demonstrated excessive PAX4 in GC tissues. (D) Overexpression of PAX4 mRNA levels were identified across six GC cell lines (HGC-27, MGC803, BGC-823, SGC-7901, AGS, MKN45) compared to the human gastric mucosal epithelial cell line GES-1. (E) The overall survival analysis results demonstrated that PAX4 high expression in GC is associated with poor prognosis.
