Research Paper
Exosomal miR-15b-5p derived from gastric cancer cells enhances immune infiltrating of tumor-associated macrophages through the WIF1/WNT5A axis
Figure 10. MiR-15b-5p targeted WIF1 and up-regulated WNT5A. (A) The combining sites between miR-15b-5p and WIF1 were predicted by the Starbase database. (B) Dual-luciferase reporter assay was conducted to verify the binding association between miR-15b-5p and WIF1. (C, D) QRT-PCR was utilized to determine the mRNA expression of WIF1 and WNT5A after transfecting miR-15b-5p mimics into THP-1 monocytes. NsP>0.05, **P<0.01, ** *P<0.001 (vs miR-NC group), N=3.