Figure 8. Knockdown of ZC3H13 or YTHDC1 promotes the malignant behavior of Ishikawa and HEC-1A cells. (A) qRT-PCR was used to determine transfection efficiency. (B) The effect of ZC3H13 or YTHDC1 expression on the proliferation of Ishikawa and HEC-1A cells was determined via EdU assays. (C) Transwell assays were used to determine the number of invading cells. Data are presented as the mean ± SEM (n = 3 per group), *P < 0.05, ** P < 0.01, *** P < 0.001 vs. the NC group.