Figure 7.Formononetin undermined activities of triple-negative breast cancer (TNBC) cells via depression of lncRNA AFAP1-AS1-miR-545/miR-195 axis. (A–C) Formononetin postponed proliferation (A), migration (B) and invasion (C) of MDA-MB-231 and BT-549 cell lines. *: P<0.05. (D) Expressions of lncRNA AFAP1-AS1, miR-545 and miR-195 were detected in MDA-MB-231 and BT-549 cell line after formononetin exposure. *: P<0.05. (E, F) Both mRNA (E) and protein (F) levels of Raf-1 and CDK4 were measured in MDA-MB-231 and BT-549 cell lines treated by formononetin. *: P<0.05.
