Figure 1. The study design. PAH: pulmonary arterial hypertension; GEO: Gene Expression Omnibus; GO: Gene Ontology; PPI: protein-protein interaction; CMap: Connectivity Map; KEGG: Kyoto Encyclopedia of Genes and Genomes; GSEA: Gene Set Enrichment Analysis; GSVA: Gene Set Variation Analysis; MTT: 3-[4,5-Dimethylthiazol-2-yl]-2,5-diphenyltetrazolium Bromide; CCK-8: Cell Counting Kit-8.