Figure 5. Functional validation assay of circRNA_102481 on EGFR-TKIs resistant cells in vitro (n=3). (A, B) MTT assay showed the effects of circRNA_102481 on EGFR-TKIs resistant cell proliferation. (C, D) Annexin V/PI assay showed the effects of circRNA_102481 on EGFR-TKIs resistant cell apoptosis. si-circRNA_102481: siRNA targeting circRNA_102481. **p<0.01 versus si-NC group.