Figure 3 — 5-Lipoxygenase inhibition reduces inflammation and neuronal apoptosis via AKT signaling after subarachnoid hemorrhage in rats

Research Paper|Volume 13, Issue 8|pp. 11752–11761

5-Lipoxygenase inhibition reduces inflammation and neuronal apoptosis via AKT signaling after subarachnoid hemorrhage in rats

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Figure 3.Zileuton suppresses expression of NF-κB, LTB4, TNF-α, IL-1β and IL-6 after SAH. (A, B) Representative images and the quantitative analysis of NF-κB after SAH in rats treat with Zileuton with or without LY294002 (n = 6 per group). (C–F) Effect of Zileuton with or without LY29400 on expression of LTB4, TNF-α, IL-1β and IL-6 after SAH (n = 6 in each group). ^*P < 0.05 vs sham group and ^&P < 0.05 vs SAH group, ^#P < 0.05 vs SAH + Zileuton group.