Transcriptome and lipidome profile of human mesenchymal stem cells with reduced senescence and increased trilineage differentiation ability upon drug treatment

Yue Chen; Xinglan An; Zengmiao Wang; Shuanghong Guan; Hongyu An; Qingyuan Huang; Haobo Zhang; Lin Liang; Bo Huang; Huiyu Wang; Min Lu; Huan Nie; Jun Wang; Xiangpeng Dai; Xin Lu

doi:doi:10.18632/aging.202759

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Research Paper Volume 13, Issue 7 pp 9991—10014

Transcriptome and lipidome profile of human mesenchymal stem cells with reduced senescence and increased trilineage differentiation ability upon drug treatment

Figure 6. Patterns of the Lipid fluctuation in drug treatment cells along 7 time points, and each data point is the log2 (fold-change) of a lipid between a drug and control. The black line shows the overall trend of the cluster. (A), (B), (C), (D) showed the trends of non-FFAs in cells treated by Metformin, Oltipraz, Rapamycin and Vitamin C, respectively. (E), (F), (G), (H) presented the trends of FFAs in cells treated by Metformin, Oltipraz, Rapamycin and Vitamin C, respectively.