Mucin 4 mutation is associated with tumor mutation burden and promotes antitumor immunity in colon cancer patients

Linglong Peng; Yang Li; Haitao Gu; Ling Xiang; Yongfu Xiong; Rong Wang; He Zhou; Jijian Wang

doi:doi:10.18632/aging.202756

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Research Paper Volume 13, Issue 6 pp 9043—9055

Mucin 4 mutation is associated with tumor mutation burden and promotes antitumor immunity in colon cancer patients

Figure 2. Gene mutations are associated with TMB. (A) Venn diagram shows 17 frequently mutated genes covered by both the TCGA and ICGC cohorts. (B) Sixteen genes with high mutation frequency are associated with a higher TMB. ^*p < 0.05; ^**p < 0.01; ^***p < 0.001; ns: no significance.