Expression of Concern
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
This article is currently under investigation. We strongly recommend that this article is not cited until the investigation is completed.
Research Paper Volume 13, Issue 7 pp 9911—9926
Exosomes derived from microRNA-512-5p-transfected bone mesenchymal stem cells inhibit glioblastoma progression by targeting JAG1
Figure 7. BMSC-exosomal miR-512-5p inhibits tumor growth in vivo. (A) Effect of BMSC-exosomal miR-512-5p as determined by HE in nude mice. (B) JAG1 and Ki-67 expression as determined by IHC. (scale bar = 50 μM) (C) Tumor growth as determined by bioluminescence imaging. after treatment with PBS or BMSC-derived exosomes. (D) Overall survival of nude mice receiving treatment was determined by Kaplan-Meier analysis. (n = 15, respectively). (*p = 0.0184, comparing the BMSC-Control-Exo group with the PBS group, #p = 0.0036, comparing the BMSC-miR-512-5p-Exo group with the PBS and BMSC-Control-Exo groups, Log-Rank test).