Figure 8 — Long non-coding RNA DPP10-AS1 exerts anti-tumor effects on colon cancer via the upregulation of ADCY1 by regulating microRNA-127-3p

Research Paper|Volume 13, Issue 7|pp. 9748–9765

Long non-coding RNA DPP10-AS1 exerts anti-tumor effects on colon cancer via the upregulation of ADCY1 by regulating microRNA-127-3p

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Figure 8.Potential molecular mechanism of the DPP10-AS1/miR-127-3p/ADCY1 axis in CCSCs. In CCSCs, upregulation of DPP10-AS1 inhibits the expression of miR-127-3p to increase ADCY1 expression, thereby inhibiting CCSC sphere and colony formation, proliferation, migration and invasion and promoting the apoptosis.