Research Paper Volume 13, Issue 7 pp 9613—9626

Hypoxia-induced microRNA-155 overexpression in extracellular vesicles promotes renal cell carcinoma progression by targeting FOXO3

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Figure 5. EV-derived miR-155 alters 786-O and Caki-1 cell proliferation. (A, B) Confirmation of miR-155 mimic and inhibitor transfection in 786-O and Caki-1 Cells. (C) The impact of miR-155 on 786-O and Caki-1 cell viability was assessed using EVs from cells prepared in A and B. EV-derived miR-155 enhances cellular viability. This experiment was conducted using three distinct biological replicates. *P < 0.05.