Research Paper Volume 13, Issue 6 pp 8895—8915

Licochalcone A improves the cognitive ability of mice by regulating T- and B-cell proliferation

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Figure 2. Analysis of the mechanism by which LA regulates the immune system conducted using RNA-seq in the hippocampus. (A) Kegg pathway classification map. (B) Bubble diagram showing the pathways regulated by LA. (C) Heatmap showing the differentially expressed genes related to the IL-17 signaling pathway. The data are presented as the mean±SD of three independent experiments. Statistical significance was determined using unpaired t-tests. *p < 0.05, **p < 0.01 compared with the Ctrl group.