Figure 4. Relationship between the Claudin family and the NPI criterion. (A) CLDN1; (B) CLDN3; (C) CLDN4; (D) CLDN5; (E) CLDN6; (F) CLDN7; (G) CLDN9; (H) CLDN10; (I) CLDN11; (J) CLDN12; (K) CLDN23. Global differences between the groups were assessed by Welch’s test, and p < 0.05 was considered significant, with Dunnett’s Tukey–Kramer test computed for each pairwise comparison. Abbreviation: NPI, Nottingham Prognostic Index.