Figure 1. Glutamine, fatty liver disease and aging. Non-alcoholic steatosis is characterized by decreased serum glutamine and increased expression of hepatic glutaminase. Aging, the most common cause of non-alcoholic fatty liver (NAFLD) and NASH is also characterized by low serum glutamine levels. The relationship between serum glutamine, aging and fatty liver remains to be unraveled. Figure created with BioRender.com.