Research Paper Volume 13, Issue 5 pp 7570—7588
Low expression of NLRP1 is associated with a poor prognosis and immune infiltration in lung adenocarcinoma patients
Figure 5. Correlations of NLRP1 expression with immune infiltration levels in LUAD. (A, B) The expression levels of NLRP1 in the TCGA-LUAD and GSE72094 datasets had significant positive correlations with the infiltration levels of B cells, CD4 T cells, CD8 T cells, dendritic cells, macrophages and neutrophils. (C, D) The expression of NLRP1 had a significant positive correlation with the immune score of LUAD samples based on the ESTIMATE algorithm in the TCGA-LUAD and GSE72094 datasets. (E, F) Kaplan-Meier survival curve analysis showed that patients with a higher immune score had longer overall survival time than those with a lower immune score in the TCGA-LUAD and GSE72094 datasets. (G, H) Kaplan-Meier survival curve analysis showed that patients with a higher NLRP1 expression level had longer overall survival time than those with a low expression level in the TCGA-LUAD and GSE72094 datasets.