ALDH2 protects naturally aged mouse retina <i>via</i> inhibiting oxidative stress-related apoptosis and enhancing unfolded protein response in endoplasmic reticulum

Pan Long; Mengshan He; Weiming Yan; Wei Chen; Dongyu Wei; Siwang Wang; Zuoming Zhang; Wei Ge; Tao Chen

doi:doi:10.18632/aging.202325

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Research Paper Volume 13, Issue 2 pp 2750—2767

ALDH2 protects naturally aged mouse retina via inhibiting oxidative stress-related apoptosis and enhancing unfolded protein response in endoplasmic reticulum

Figure 1. The expression of ALDH2 in the young (WT) group, aged (WT) group and aged (ALDH2+) group. (A, B) A typical ALDH2 WB image and the expression of ALDH2; (C, D) A typical ALDH2 immunofluorescence image and the expression of ALDH2. All analyses were performed in duplicate. Scale bar: 50 μm. Values are presented as the mean ± SD, n = 4 mice per group. *P<0.05: aged (WT) group and aged (ALDH2+) group vs young (WT) group; ^#P<0.05: aged (ALDH2+) group vs aged (WT) group.